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br Conclusions The experimental results in
2019-04-15
Conclusions The experimental results in isolated sheep hearts presented herein clearly demonstrate that self-sustained rotors exist in the atria. Such rotors are the high frequency sources that give rise to the complex patterns of activation that characterize AF. More specifically, our results su
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br Does ambulatory monitoring prevent HF decompensation Whil
2019-04-15
Does ambulatory monitoring prevent HF decompensation? While vigilant monitoring of symptoms and signs (and BNP levels) is useful, it does not guarantee the accurate prediction of ADHF. On the other hand, frequent monitoring of some of these signs and symptoms and the use of external physiological
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In advanced GIST patients where a course of treatment of
2019-04-15
In advanced GIST patients where a course of treatment of Imatinib is interrupted by disease progression, subsequent rechallenge with Imatinib restored tumor control in most patients. In the prospective BFR14 trial, 25 patients with disease progression after interruption of one year of treatment rest
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The outcome of sinus node modification with
2019-04-15
The outcome of sinus node modification with radiofrequency ablation has been reported, but it involves a high invasive risk associated with the ablation. Thus, careful confirmation of the earliest activation site and ablation of that site is important [2,3]. The clinical use of the 3D-mapping system
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The predicted mean time to attaining
2019-04-15
The predicted mean time to attaining the maximal indirect impact is relevant when considering adult vaccination with PCV. Most developed countries do not recommend PCV in adults, believing that with the high coverage in the infant programme, adult disease will (eventually) decline. The US vaccine de
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Paisey et al recently proposed
2019-04-15
Paisey et al. recently proposed a simple technique for recognizing an MI block. In their study, an abrupt change of the CS activation pattern during RF application, under left atrial appendage pacing from a distal-to-proximal to proximal-to-distal direction provided a reliable assessment of MI condu
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Hypocretinergic activation during REM sleep
2018-11-15
Hypocretinergic activation during REM sleep is likely related to the activation that occur during certain patterns of somatomotor activity [50]. Although motor output is inhibited at the motoneuron level during REM sleep, supraspinal motor systems are very active during this state [60–62]. In fact,
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Obstructive sleep apnoea hypopnoea syndrome OSAHS affects
2018-11-15
Obstructive sleep apnoea hypopnoea syndrome (OSAHS) affects 2–4% of middle-aged adults [1–3]. It is associated with various adverse cardiovascular outcomes [4,5] and appears an independent factor for arterial [6] and possibly venous thrombosis [7]. However, studies focusing on mechanisms to explain
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Las variaciones de los precios de los bienes agropecuarios n
2018-11-15
Las variaciones de los precios de los bienes agropecuarios no afecta mucho las variaciones de la demanda, éstas dependen más de las variaciones del ingreso, de su distribución y de los cambios en el patrón de consumo. En efecto la demanda de bienes alimentarios agropecuarios es inelástica dentro de
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El problema de la deuda
2018-11-15
El problema de la deuda El rescate de Grecia por parte de la Troika empezó en mayo de 2010 cuando se le otorga un primer préstamo de aproximadamente 240 mil millones de euros, dado que en octubre de 2009 se descubren las verdaderas cifras del nivel de la deuda pública de Grecia; además de este prés
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Three additional assumptions are made the probability of
2018-11-15
Three additional assumptions are made: the probability of apprehension is assumed to increase monotonically with the spending in private protection (i.e. p=p(e), where p′>0); victims and criminals are considered as risk-neutral; criminals are assumed to have complete information in that they observe
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Such contradictory results motivate Furlani et al
2018-11-15
Such contradictory results motivate Furlani et al. (2008) to estimate a reaction function for the Brazilian Central Bank using the Bayesian method. The question to be answered was very direct. Does the Central Bank alter its conduct on monetary policy due to changes in the exchange rate? The reporte
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Introduction The monthly continuous inflation rate that maxi
2018-11-15
Introduction The monthly (continuous) inflation rate that maximizes the inflation tax revenue varies widely (from 18.3% to 143%), according to semi-elasticity estimates for the German hyperinflation made by several authors (Cagan, 1956; Barro, 1970; Frenkel, 1977; Sargent, 1977; Goodfriend, 1982; B
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AMG 925 In addition while a general biomarker hypothesis
2018-11-15
In addition, while a general biomarker AMG 925 was stated in the protocol, the specific biomarker (i.e., HRG mRNA) and a description of the validated assay were defined only in the statistical analysis plan. An alternative approach would have been to amend the protocol once the preclinical data and
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br Materials and Methods br
2018-11-15
Materials and Methods Results Discussion Our previous studies in mice with germline or induced ablation of SHIP1 expression suggested that chemical inhibition of SHIP1 in vivo might recapitulate genetic phenotypes that reduce the immune barrier to allogeneic HSCT and or enhance mobilization
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