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br Conflict of interest br Acknowledgments
2019-05-30
Conflict of interest Acknowledgments Background of basic genetics The human genome contains approximately 3 billion nucleotide ion channel pairs contained in 23 chromosome pairs. Each chromosome contains hundreds to thousands of genes and the estimated 30,000 genes in the human genome expr
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It must be noted that modern physical techniques for structu
2019-05-30
It must be noted that modern physical techniques for structural analysis of steroids were not available to these early talented scientists that time. It was a challenging task for these early scientists to precisely identify the chemical structures of cholesterol and bile acids. However, the develop
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The conventional cutoff for small for
2019-05-30
The conventional cutoff for small for gestational age is based on birthweight, which is suitable for infants born at term but is far less appropriate for those born preterm. Preterm birth is itself pathological, and ultrasound-based estimates of fetal weight show that infants born preterm are much s
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br Conclusion br Introduction Multiple
2019-05-29
Conclusion Introduction Multiple myeloma is a malignant plasma cell disorder, comprising approximately 10% of all haematological malignancies, and its incidence is increasing [1]. The pathogenesis is complex, culminating in malignant transformation of clonal plasma cells. The aetiology is not
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The extraction of primary teeth
2019-05-29
The extraction of primary teeth has shown a significant upward trend since 2011, and after 2012, these numbers showed a significant difference compared with 2006. One possible explanation for this ghrelin receptor was the high failure rate of upper anterior composite resin strip crowns placed over
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Fig shows different PVCs observed before PVC and
2019-05-29
Fig. 4 shows 2 different PVCs observed before (PVC 1) and after the application of radiofrequency cerk (PVC 2) in patient 17. After ablation of PVC 1, a different PVC (PVC 2) with a slightly different QRS morphology from that of PVC 1 was observed. Fig. 5 shows the activation sequence of PVC 1 and
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br Conclusion br Conflict of interest statement
2019-05-29
Conclusion Conflict of interest statement Authors\' contribution Introduction There are two classes of bisphosphonates that differ with regard to structure and mechanism of action [1]. The first one includes pyrophosphate-resembling bisphosphonates, such as clodronate and etidronate, whi
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This is similar to the z score with
2019-05-29
This is similar to the z score, with the mean intra-sample correlation providing a “population mean”. A score greater than −1 was considered a good match (1 point), a score greater than −2 was a partial match (0.5 points), and a score less than −2 was no match (0 points). Spatial resolution was then
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herpes simplex virus br Materials and methods br Results
2019-05-29
Materials and methods Results Discussion Our results demonstrated that patients who underwent ICD implantation and received 15J-DT exhibited evidence of myocardial damage as indicated by increased serum c-TNT and H-FABP levels. On the other hand, ≤10J-DT (9J or 10J) was associated with an a
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Sin embargo no se puede hablar de etapas delimitadas con
2019-05-29
Sin embargo, no se puede hablar de etapas delimitadas con absoluta precisión; la revista Simpleton, en 1998, en un artículo que aparece sin firma, apunta que en la década de los veinte no se ignoraba si ganaría la batalla de la prosa americana el adornado estilo de Fitzgerald o la musculosa dicción
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Among patients with established infection in the
2019-05-28
Among patients with established infection in the bone or surrounding tissue (Stage II) antibiotic penicillin-based therapy in addition to mouthwash may result in healing in patients with minor ONJ lesions. However, a large proportion of cases tend to show chronically infected necrotic process in jaw
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Repurposing use of approved drugs for new indications
2019-05-28
Repurposing (use of approved drugs for new indications) or repositioning (use of drugs whose development was not continued for new indications) of existing drugs has been put forward as a method to overcome some of these issues. Indeed, drug repositioning and repurposing could lead to higher rates o
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Studies of strategies to reduce greenhouse gas emissions and
2019-05-28
Studies of strategies to reduce greenhouse gas emissions and improve health in urban environments have shown the potential to achieve both environmental and health improvements. For example, modelled effects of low emission vehicles and increased walking and cycling in London and Delhi showed major
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It is established that hypoxia can induce autophagy We
2019-05-28
It is established that hypoxia can induce autophagy [32,34–37]. We evidenced the autophagic activation in the cultured human osteosarcoma MG-63 dapt secretase after incubation in 1% O2 for 24h. The concomitantly elevated LC3 protein levels with HIF-1α high expression on OS tissue sections also indi
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Causative genes for ARVC and their
2019-05-27
Causative genes for ARVC and their respective characteristics are summarized in Table 1. Desmosome genes for ARVC Other causative genes for ARVC Although more than half of ARVC patients carry mutations in desmosome genes, other genes have also been reported as causative genes for ARVC (Table
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