• It is important to note that the financial crisis

  2018-11-05

  

  It is important to note that the 2009 financial crisis brought about one of the highest unemployment rates in Western Europe (Arpaia & Curci, 2010). According to the most recent estimates, the unemployment rate in France is still above 10%, which is more than double that of the rate in the United Ki

• br Literature review br Research design

  2018-11-05

  

  Literature review Research design Analysis and results The data analysis will consist of exploring the statistical properties of all the items of the scales and testing the validity and reliability of the constructs (Gallarza & Gil, 2006). We will verify the reliability through the inter-it

• One way around this problem is to

  2018-11-05

  

  One way around this droperidol problem is to build an empirical model which relates the bulk moduli to some other physical properties of some materials with the same crystal structure but different compositions (Anderson and Anderson, 1970; Duffy and Anderson, 1989). By extending the ranges of all t

• br Limitations Though the use of organ or

  2018-11-05

  

  Limitations Though the use of organ- or tissue-on-a-chip devices shows a great deal of promise for future applications, it is important to remember that these are relatively new technologies and require further advancements prior to widespread use. It is first necessary to characterize these devi

• Gut Microbiome and Inflammatory Bowel Disease

  2018-11-05

  

  Gut Microbiome and Inflammatory Bowel Disease Modulation of Gut Microbiota in Obesity and Cardiometabolic Disorders Changes in gut microbiota are associated with metabolic disorders such as obesity, type 2 diabetes and cardiovascular risk factors. Patrice D. Cani (Brussels, Belgium), Willem M. d

• In summary we here provide insights into questions raised as

  2018-11-05

  

  In summary, we here provide insights into questions raised as a result of clinical experiences: How does clevidipine cause dyspnea relief in hypertensive AHF? What explains the specificity of this effect for clevidipine and not for other DHPs? What underlies the apparent potency differences between

• Polyubiquitylation leading to proteolytic degradation

  2018-11-05

  

  Polyubiquitylation leading to proteolytic degradation by the 26S proteasome is involved in all aspects of cell physiology. The highly coordinated process ensures the selective and timely turnover of proteins, thereby controlling cellular activity and maintaining cell and tissue homeostasis (Glickman

• We have previously reported that Nef activates and

  2018-11-05

  

  We have previously reported that Nef activates and shuttles activated ADAM17 into extracellular vesicles (EV) (Lee et al., 2013). This occurred through interaction with a multifaceted protein complex termed the Nef-associated kinase complex (NAKC). In more recent results we demonstrated that Nef/ADA

• Given the competing roles described above an

  2018-11-05

  

  Given the competing roles described above, an important question is whether treatment of cancer by autophagy inhibition will lead to neurodegenerative side effects and likewise, that treatment of neurodegenerative diseases with autophagy promoting agents might promote pre-malignant tumors. There are

• a01 br Definition of local product Thilmany et al suggested

  2018-11-05

  

  Definition of local product Thilmany et al. (2008) suggested that the importance of the ‘local food’ movement was manifested by the selection of ‘Locavores’ in 2007 as the word of the year by the New Oxford American Dictionary, which defines the term as a resident who tries to consume food produc

• Another relevant factor that contributes to the development

  2018-11-05

  

  Another relevant factor that contributes to the development of metabolic disturbances associated with sleep restriction is energy expenditure. Individuals who sleep less are more likely to experience fatigue and sleepiness during the day, which may discourage them from daytime physical activity and

• BKM120 Bedtime and wake time were not related to overweight

  2018-11-05

  

  Bedtime and wake time were not related to overweight or obesity in our study, however an EL sleep timing behavior, corresponding to a longer duration of sleep, resulted in a better weight control compared to the others sleep timing behaviors. In a recent Australian cross-sectional study, adolescent

• br Methods br Sleep and immunity For over years

  2018-11-05

  

  Methods Sleep and immunity For over 2000 years the relationship between sleep and immunity has been the subject of discussion. Hippocrates, for example, mentioned the presence of sleepiness during the course of an acute infection [18,20]. Today we know that the interaction between sleep and i

• br Materials and methods Adult Cebus apella males from

  2018-11-05

  

  Materials and methods Adult Cebus apella males from the Tufted Capuchin Procreation Center (UNESP, Campus Araçatuba) were housed in the same conditions, in individual cages and subjected to natural light-dark (LD) cycles. Eleven monkeys were sacrificed at different times (one animal at each time

• br Various modeling and simulation routes In Fig the various

  2018-11-05

  

  Various modeling and simulation routes In Fig. 1 the various routes for modeling/simulation of a gas sensor are identified. Computational software program such as Matlab/Mathematica can be used for simulating chemisorption induced surface bending, surface potential and theoretical verification of

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