• Introduction The majority of induced pluripotent

  2018-10-26

  

  Introduction The majority of induced pluripotent stem cells (iPSCs) are not fully reprogrammed (Chan et al., 2009; Lee et al., 2013; Mikkelsen et al., 2008). There is still minimal information on transition checkpoints necessary to induce full reprogramming. Pluripotent stem cells (PSCs) have funct

• A better understanding of pluripotent state of zebrafish emb

  2018-10-26

  

  A better understanding of pluripotent state of zebrafish embryos allows us to accurately induce differentiation to cardiomyocytes from primary embryonic cells. A central feature of our method is the use of a combination of appropriate conditions including cell density, ZF4 feeder cells, and suppleme

• br Results br Discussion We report the development of a

  2018-10-26

  

  Results Discussion We report the development of a method to generate and proliferate iCx26GJCs from mouse iPSCs for use as a disease model and in inner-ear cell therapies targeting GJB2-related hearing loss, the most frequent type of hereditary deafness worldwide. Our induction method until da

• The results also highlight the value

  2018-10-26

  

  The results also highlight the value of thinking about gender-based educational disparities in broader terms than school participation alone. In many low-income contexts, the rapid increase in enrollment has been at the expense of school quality (Pritchett, 2013), and, compared to boys, girls’ schoo

• br Acknowledgements This work was supported by the Bill and

  2018-10-26

  

  Acknowledgements This work was supported by the Bill and Melinda Gates Foundation [OPP10327313]; Eunice Shriver Kennedy National Institute of Child Health and Development [R01 HD070993]; and Grand Challenges Canada [Grant 0072-03]. The data used in this study come from Young Lives, an internation

• br Theoretical foundation of the study br

  2018-10-26

  

  Theoretical foundation of the study Methodology A Web-based survey was distributed to 3060 international and/or general manager in charge of the firm\'s foreign business activity of Spanish exporting firms in the food sector, beverage sector, consumer goods, raw materials, industrial products

• br Acknowledgement The authors thank financial support

  2018-10-26

  

  Acknowledgement The authors thank financial support from Visveswaraya Technological University, Belagavi, Karnataka, India, under VTU research Grants Scheme-2010-11 (VTU/Aca./2011-12/A-9/6380). Introduction Liquid–liquid extraction is the second most important Phos-tag Acrylamide process larg

• Gaikwad and Gupta associate acid mine drainage

  2018-10-26

  

  Gaikwad and Gupta (2008) associate angiopoietin mine drainage, also known as abandoned mine drainage, to the reaction of water and oxygen specifically with coal mining. Water passing through the rocks from mining operations that have been deposited on the surface and the underground voids left behi

• At months of age no obvious physical

  2018-10-26

  

  At 51 months of age, no obvious physical abnormalities were found. Kampo (yokukansan) showed no effect but clonazepam (0.1–0.2mg) showed favorable effects on the intensity and frequency of arm banging. We have attempted to increase the dose of clonazepam gradually, but no complete remission has been

• br Detection of IFL Assessing

  2018-10-26

  

  Detection of IFL Assessing for inspiratory flow limitation requires recognition of both flow and intrathoracic pressure changes [21]. A decrease in flow normally is accompanied by a compensatory increase in intrathoracic pressure. This is illustrated in Fig. 1 in the setting of differentiating a

• Consumption of mg day of caffeine was

  2018-10-26

  

  Consumption of 200mg/day in the remaining 97 (13%). The main source of caffeine intake was coffee, which was most often consumed early in the morning and in the late afternoon. Overall, 115 (16%) individuals admitted daily ingestion of ≥2 cups of coffee, 267 (37%) between 1 and 2 cups, 147 (21%) les

• About a third of epileptic patients present seizures during

  2018-10-26

  

  About a third of epileptic patients present seizures during sleep [51]. Sleep can activate the occurrence of seizures and electroencephalogram (EEG) abnormalities [52]. Van Golde refers that during NREM (non-rapid eye movement) sleep discharges are facilitated (most likely for the synchronized patte

• Introduction The Institute of Medicine estimated that as

  2018-10-26

  

  Introduction The Institute of Medicine estimated that as many as 98,000 patients die each year due to preventable medical errors, making this the sixth leading cause of death in the United States, and claiming more lives than diabetes or Alzheimer disease [1]. Additionally, the expense of medical c

• The above illustrations of the

  2018-10-26

  

  The above illustrations of the possibility to trigger and monitor viscosity evolution of molecular reactions using a simple physical science method open up a wider array of biological or biomedical applications to directly monitor, for instance, the effect of a drug such as warfarin on blood viscosi

• br Materials and methods br Results and discussion br

  2018-10-26

  

  Materials and methods Results and discussion Acknowledgments This research was supported in part by NSF through the Partnership for Research and Education in Materials grant (DMR-0611539). Core research facilities were supported by grants from the NSF (CHE-0840450) and NIH (NCRR 8G12MD00758

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