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br Results br Discussion br Conclusions In summary this stud
2024-01-29
Results Discussion Conclusions In summary, this study provides novel report of pericardial adipose aromatase expression – in both human and rodent. We show that aromatase expression is remarkably upregulated with aging (Fig. 1C), and that total aromatase PXD101 conversion capacity is signi
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The alamarBlue test revealed that recombinant apelin
2024-01-29
The alamarBlue test revealed that recombinant apelin led to an increase in basal and IGF1- and FHS-induced ovarian cell proliferation. Apelin increased ERK1/2 and Akt protein expression, but cell proliferation returned to control levels in the presence of kinase inhibitors. This suggests that the pr
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Furthermore because most of foods and beverages have been co
2024-01-29
Furthermore, because most of foods and beverages have been consumed after processing, researchers have focused on the effects of processing (e.g. blanching, cooking, drying, cooling, freezing, high-pressure treatment, pulsed electric field) on total antioxidant capacity of foods. In general, there w
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Recently whey products have been added to nutritional
2024-01-29
Recently, whey products have been added to nutritional beverages to boost their antioxidant capacity. Supplementation of a lemon drink with 1% WP hydrolyzed by subtilisin increased the antioxidant activity of the beverage from 0.75 to 7.79 mmol of TE/L (Athira et al., 2014). In addition, a flavored
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br Natriuretic peptides and neprilysin
2024-01-29
Natriuretic peptides and neprilysin Left ventricular systolic function, most commonly due to myocardial damage as a consequence of coronary artery disease, hypertension or both, and leading to sustained, pathological activation of the renin angiotensin AZD6738 australia system (RAAS) and sympath
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Earlier studies with SERMs identified that distinct chemical
2024-01-29
Earlier studies with SERMs identified that distinct chemical scaffolds have the ability to induce unique conformational changes in the ER, resulting in interaction with different cofactor subsets. The same has been demonstrated with SARMs, which induce distinct conformational changes compared to tes
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It was reported that oral
2024-01-29
It was reported that oral administration of CSZ to C57BL/6J mice significantly improved spatial learning and memory, and prevented Aβ-induced immunoresponse in Aβ25-35-injected mice. However, post-treatment with CSZ after Aβ25-35 administration, when Aβ was already accumulated, did not prevent Aβ-in
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The reaction of LOX with unlabeled AA
2024-01-27
The reaction of 5-LOX with unlabeled AA generated products from hydrogen abstraction at C7 (95% 5-HETE) with minor products derived from abstraction at C10 (5% 8-HETE). With 7,7--AA the selectivity remained skewed towards C7 hydrogen abstraction (59%) compared to C10 hydrogen abstraction products (4
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CK is considered a central controller of cellular
2024-01-27
CK is considered a central controller of cellular energy homeostasis that catalyzes the reversible transfer of a phosphoryl group from ATP to adenosine diphosphate (ADP) and creatine to produce PCr [5]. This enzyme builds up a large pool of rapidly diffusing PCr for temporal and spatial buffering of
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br Concluding remarks It is clear that a
2024-01-26
Concluding remarks It is clear that a disordered l-arginine homeostasis by changes in arginase, NOS and ADMA activity and expression, is not only vital in the chronic airway diseases, mct inhibitor and COPD, but also seems to play an important role in many co-morbidities. Unknown, however, is wh
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Later on Wayner Burton Ingold Barclay
2024-01-26
Later on, Wayner, Burton, Ingold, Barclay, and Locke (1987) modified the method by using lipid to examine the ability of an antioxidant S63845 protect against lipid peroxidation generated by azo-compound. It was later improved using β-phycoerythrin (β-PE) as a fluorescent probe, and the ability of
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The functional significance of the
2024-01-26
The functional significance of the cap residues with regard to the established role of PfA-M1 in hemoglobin catabolism in the food vacuole is a key question that is difficult to address with in vitro studies. We note that three of the dipeptide substrates used in our study are found in the sequences
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Based on our findings in this work as
2024-01-26
Based on our findings in this work as well as the previous published data in the experimental mice model of RSV infection, we suggest that modulation of 12/15 LOX expression and/or blocking of LOX products such as 12(S)-HETE may represent potential pharmacological approaches to prevent or treat vira
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A previous study reported that the serotonergic mechanism wa
2024-01-26
A previous study reported that the serotonergic mechanism was involved in the psychological stress-induced alteration in synaptic plasticity in the rat hippocampal CA1 field (Matsumoto et al., 2004). Sumitaka Inoue et al. (Inoue et al., 2014) reported that pretreatment with a 5-HT1A receptor partial
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br Results br Discussion Today enzymes play important
2024-01-26
Results Discussion Today, enzymes play important roles in various fields. A good assay for enzyme activity is of great value, especially when it has good specificity, sensitivity, reproducibility and economy. ADK is the first identified enzyme in the metabolic pathway of adenosine salvage [15,
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