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br Dihydrotestosterone in adult fish
2024-02-18
Dihydrotestosterone in adult fish and frogs New perspectives and next directions Similar to other androgens, DHT can modulate reproductive endpoints in both fish and amphibians. However, predicting the effects of DHT can be challenging, as reproductive homeostasis is dependent upon the balance
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In this study significant reduction in
2024-02-18
In this study, significant reduction in the HCO3− content in sham-operated and testosterone-treated rats following bafilomycin A1 administration suggested that V-ATPase could be involved in mediating the decrease in vas deferens fluid HCO3− content, most probably due to the increase in H+ secretion
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The resolution cocrystal structure of
2024-02-18
The 2.10Å resolution cocrystal structure of ACL in complex with citrate indicates that the carboxyl (COH) groups of citrate forms a network of H-bonds with hydrophilic residues surrounding the ACL citrate binding domain (CBD) (A). The - carboxyl group forms a salt bridge with the guanidine moiety of
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br Materials and methods br Results br Discussion
2024-02-18
Materials and methods Results Discussion In the present study, we found that SSTR2, SSTR5, and DA2R proteins are expressed in ACTH-positive Spectinomycin hydrochloride hydrate in healthy canine pituitary glands, with particularly high positive cell ratios in the intermediate lobes. Somatos
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br Experimental section br Acknowledgments br Introduction A
2024-02-18
Experimental section Acknowledgments Introduction Adipose is a major endocrine organ which releases a range of bioactive agents [1]. Selected adipose depots have been established as sites of sex steroid metabolism [1]. Subcutaneous and visceral adipose express high levels of aromatase, cap
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By contrast with a plenty of
2024-02-18
By LY 294002 with a plenty of our understanding on arginine metabolism in animals and higher plants, very little thus far is known on the specific function of arginase that acts as a key control point for keeping arginine balance in edible mushrooms and neither for its physiological role in posthar
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br Materials and methods br
2024-02-18
Materials and methods Results Discussion In this study, we administrated BDE-153 to newborn rat pups at PND 10 and cultured primary neurons, measured neuronal apoptosis and LDH activity in vivo and in vitro, then explored the possible predominant pathway underlying the neuronal apoptosis by
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br Results and discussion The soil fungus PSU RSPG BCC
2024-02-18
Results and discussion The soil fungus PSU-RSPG37 (BCC56870) was isolated from soil samples collected from Rajjaprabha Dam, Suratthani Province, Thailand. The fungus was deposited at BIOTEC Culture Collection, National Center for Genetic Engineering and Biotechnology (BIOTEC), Thailand Science Pa
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Cy5 maleimide (non-sulfonated) We report here the first stud
2024-02-18
We report here the first study on the inhibitory effects of the organic nitrates – on human erythrocyte GR. The previous reports by Becker et al., investigated other nitro derivatives (including arylizoalloxazines) by using Beutler’s method, monitoring GR inhibition. Data of show inhibition of hGR b
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br Acknowledgements The authors would like
2024-02-14
Acknowledgements The authors would like to thank Dr. Bradford B. Lowell for providing us with β-less and WT breeding pairs. Funding sources: This work was supported by NIH Grant DK028082 (to E.M.F) and by an Institutional Research Training Grant NRSA 5T32DK751627 (to N.D.). Introduction The e
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The activation of the A BR
2024-02-14
The activation of the A2BR subtype triggers different intracellular metabolic pathways, often linked to the activation of adenylyl cyclase and increased levels of intracellular cAMP (Lynge et al., 2003, Bernareggi et al., 2015). The nAChR-channel cftr mediated by the cAMP/PKA pathway was reported t
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Double immunofluorescence staining of Gas and Axl with neuro
2024-02-14
Double immunofluorescence staining of Gas6 and Axl with neuronal specific nuclear protein (NeuN), glial fibrillary acidic protein (GFAP), and ionized calcium-binding adaptor molecule 1 (Iba-1), demonstrated that Gas6 and Axl are expressed by neurons, astrocytes and microglia/macrophages (Fig. 2). In
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Introduction Inflammasomes are large cytosolic protein compl
2024-02-09
Introduction Inflammasomes are large cytosolic protein complexes with multiple components that trigger a rapid immune response against pathogen-associated molecular pattern colorimetric (PAMPs) during pathogen infections or damage-associated molecular pattern molecules (DAMPs) during tissue damage
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We found evidence of the interaction between AR and hemiacet
2024-02-09
We found evidence of the interaction between AR and hemiacetals by evaluating the effect of glucose on l-idose reduction. l-idose was recently proposed as the best AR substrate able to mimic glucose [38]. This aldose is structurally very closely related to d-glucose, from which it differs only in th
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Implicit in this concept is the idea that the adrenoceptors
2024-02-09
Implicit in this concept is the idea that the β-adrenoceptors in the detrusor would be activated by adrenergic nerves of the sympathetic system: sympathetic activity promoting relaxation and enhancing bladder capacity. However, it has been demonstrated that there is only a sparse adrenergic innervat
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